New Yorker reporter Dhruv Khullar spotlights how researchers from across MIT are using AI to advance drug development. Khullar highlights the MIT Jameel Clinic, the Broad Institute and various faculty members for their efforts in bridging the gap between AI and drug research. “With AI, we’re getting that much more efficient at finding molecules—and in some cases creating them,” says Prof. James Collins. “The cost of the search is going down. Now we really don’t have an excuse.”
Associated Press reporter Bernie Wilson spotlights Christina “Chris” Birch PhD '15 and her quest to reach outer space after conquering many miles as a competitive cyclist. “Birch’s resume is staggering,” Wilson notes. “In cycling, she has 11 national championships as well as multiple Pan American and World Cup medals. She has degrees in mathematics, biochemistry and molecular biophysics, and a doctorate in biological engineering from MIT.” Of her outer space aspirations, Birch explains: “While I would love to be a scientist on the moon, doing research, collecting samples, just to be a part of our return to the moon would be incredible, because we are asking such interesting scientific questions.”
MIT scientists have shown a simple paper-strip test can detect the flu and identify the specific strain, which could prove useful in improving outbreak response and infection care, writes Dennis Thompson for HealthDay. Jon Arizti-Sanz PhD ’24 says “being able to tease apart what strain or subtype of influenza is infecting a patient has repercussions both for treating them and public health interventions.”
Prof. Sara Seager, Prof. Robert Langer and Prof. Nancy Kanwisher have been awarded the 2024 Kavli Prize for their work in the three award categories: astrophysics, nanoscience, and neuroscience, respectively, reports Michael T. Nietzel for Forbes. According to the Norwegian Academy of Science and Letters, this award honors scientists with outstanding research “that has broadened our understanding of the big, the small and the complex,” writes Nietzel.
Prof. Linda Griffith and Stuart Orkin '67 were named to this year’s Time 100 Health list, which recognizes innovators leading the way to new health solutions. Griffith, who was honored for her work engineering a uterine organoid to study endometriosis, explains that in the future engineered organoids could be used to find the most effective treatments for patients. “We have all the genetic information and all the information from the patient’s exposure to infections, environmental chemicals, and stress that would cause the tissues to become deranged in some way, all captured in that organoid,” Griffith explains.
MIT researchers have developed a new type of spring-like device that uses a flexible element to help power biohybrid robots, reports Brian Heater for TechCrunch. “The muscle fiber/flexure system can be applied to various kinds of robots in different sizes,” Heater writes, adding that the researchers are, “focused on creating extremely small robots that could one day operate inside the body to perform minimally invasive procedures.”
Nature reporter Amanda Heidt speaks with postdoctoral researcher Tigist Tamir about her experience using generative AI with attention-deficit hyperactivity disorder. “Whether I’m reading, writing or just making to-do lists, it’s very difficult for me to figure out what I want to say. One thing that helps is to just do a brain dump and use AI to create a boiled-down version,” Tamir explains. She adds, “I feel fortunate that I’m in this era where these tools exist.”
NASA astronaut Christopher Williams PhD '12 shares his excitement over the upcoming solar eclipse with Space.com Elizabeth Howell, noting he is most excited that the celestial event will provide unique views of the sun’s outer atmosphere. Williams previously conducted radio astronomy research and helped build the Murchison Widefield Array in Australia during his time at MIT. "It was an incredible experience, because I got to both work on the cosmology and the science behind that,” recalls Williams.
MIT researchers have discovered a protein found in human sweat that holds antimicrobial properties and can “inhibit the growth of the bacteria that causes Lyme disease,” reports Matt Fortin for NENC. The team believes this “type of protein could be put into a topical cream to make something called ‘Lyme Block’ – like sunblock, but for preventing Lyme.” "Ideally what we would love to do is give people more control over their own risk," says Principal Research Scientist Michal Tal. "And really try to develop this into a possible preventative that you could put on repellant or sunblock to protect against other elements of the outdoors that you could also protect yourself against Lyme."
Prof. Katharina Ribbeck speaks with Christopher Intagliata of Scientific American’s “Science Quickly” podcast about her research exploring how mucus can treat and prevent disease. “The basic building blocks of mucus that give mucus its gooey nature are these threadlike molecules—they look like tiny bottlebrushes—that display lots and lots of sugar molecules on their backbone,” explains Ribbeck. “And these sugar molecules—we call them glycans—interact with molecules from the immune system and microbes directly. And the exact configuration and density of these sugar molecules is really important for health.”
Researchers from MIT and elsewhere have isolated a “protein in human sweat that protects against Lyme disease,” reports Matthew Rozsa for Salon. The researchers believe that if “properly harnessed the protein could form the basis of skin creams that either prevent the disease or treat especially persistent infections,” writes Rosza.
Researchers from MIT and elsewhere are studying how T-cell receptors recognize antigens, reports Michael T. Nietzel for Forbes. The team “hopes to develop antigen-specific immunotherapies which could also have treatment implications for infectious diseases and allergies,” writes Nietzel.
Christina “Chris” Birch PhD '15 is among NASA’s newest class of astronauts, reports Norah O’Donnell for CBS Evening News. “These new astronauts could one day be part of the team that brings the first woman and first person of color to the surface of the moon and beyond.”
Senior Lecturer Guadalupe Hayes-Mota writes for Forbes about the ways AI is reshaping drug development. “In the next three years, we can anticipate a more streamlined, efficient and cost-effective drug development process, ultimately leading to faster access to life-saving drugs for patients worldwide,” Hayes-Mota writes. “This is not just an evolution; it is a revolution in healthcare powered by the intelligence of machines.”
Prof. Feng Zhang has been named to STAT’s 2024 STATUS List, which highlights the leaders shaping the future of health and life sciences, reports Dialynn Dwyer for Boston.com. “Among the companies he’s co-founded is Editas Medicine, which as of late 2023 was now the official holder of patent rights to the CRISPR-Cas9 gene editing tool used in the sickle cell therapy Casgevy, and Aera Therapeutics, which in February 2023 raised $193 million in venture funding to develop protein nanoparticles as a way of delivering gene editing,” Dwyer writes.