Pursuing the secrets of a stealthy parasite
By unraveling the genetic pathways that help Toxoplasma gondii persist in human cells, Sebastian Lourido hopes to find new ways to treat toxoplasmosis.
AI model identifies certain breast tumor stages likely to progress to invasive cancer
The model could help clinicians assess breast cancer stage and ultimately help in reducing overtreatment.
CHARMed collaboration creates a potent therapy candidate for fatal prion diseases
A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.
Symposium highlights scale of mental health crisis and novel methods of diagnosis and treatment
Co-hosted by the McGovern Institute, MIT Open Learning, and others, the symposium stressed emerging technologies in advancing understanding of mental health and neurological conditions.
Taking RNAi from interesting science to impactful new treatments
Alnylam Pharmaceuticals, founded by MIT professors and former postdocs, has turned the promise of RNAi research into a new class of powerful therapies.
New treatment could reverse hair loss caused by an autoimmune skin disease
A microneedle patch that delivers immune-regulating molecules can teach T cells not to attack hair follicles, helping hair to regrow.
Epigenomic analysis sheds light on risk factors for ALS
In a study of cells from nearly 400 ALS patients, researchers identified genomic regions with chemical modifications linked to disease progression.
3 Questions: A shared vocabulary for how infectious diseases spread
Lydia Bourouiba’s research on fluid dynamics influenced new guidance from the World Health Organization that will shape how health agencies respond to respiratory infectious diseases.
Improving drug development with a vast map of the immune system
Immunai’s founders were researchers at MIT when they launched their company to help predict how patients will respond to new treatments.
Unlocking mRNA’s cancer-fighting potential
MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and powerful treatments.
Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps
Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.
A protein found in human sweat may protect against Lyme disease
Researchers also found that a variant of the protein is not as protective against the bacteria and increases susceptibility to the disease.
How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice
Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.
Deciphering the cellular mechanisms behind ALS
Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.
A noninvasive treatment for “chemo brain”
Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.